The Steering Committee provides overall scientific leadership. Industry representatives to the Steering Committee will rotate on an annual (staggered) basis. (* Denotes Steering Committee co-chairs.)
| Categories | Members | Affiliations |
| Academic | Manal Abdelmalek | Mayo Clinic |
| Veronica Miller* | Forum for Collaborative Research | |
| Mazen Noureddin | Houston Research Institute | |
| Arun Sanyal* | Virginia Commonwealth University | |
| Vincent Wong | The Chinese University of Hong Kong | |
| Consortia | Quentin Anstee | Newcastle University |
| Industry | Margery Connelly | Labcorp |
| Céline Fournier | ECHOSENS | |
| Michelle Long | Novo Nordisk | |
| Bryan Rudolph | Boehringer Ingelheim | |
| Rebecca Taub* | Madrigal Pharmaceuticals | |
| Belle van Rosmalen | Eli Lilly and Company | |
| Regulatory | Ruby Mehta | U.S. Food and Drug Administration |
| Joachim Musaus | European Medicines Agency | |
| Societies & Organizations | Naga Chalasani | Indiana University School of Medicine/ AASLD |
| Wayne Eskridge | Fatty Liver Foundation | |
| Lorraine Stiehl | American Liver Foundation | |