(* Denotes Steering Committee co-chairs.)
| Categories | Members | Affiliations |
| Academic | Christopher Bowlus, MD | UC Davis Medical Center |
| Gideon Hirschfield, MA, MB, Bchir, MRCP, PhD | University of Toronto | |
| Joshua Korzenik, MD | Brigham and Women's Hospital | |
| Michael Trauner, MD* | Medical University of Vienna | |
| Doug Thorburn, MD | University College London | |
| Palak Trivedi, MBBS, MRCP Gastro (UK), PhD | University of Birmingham | |
| Patient Representatives & Advocacy | Ricky Safer | PSC Partners Seeking a Cure |
| Martine Walmsley, BSc | PSC Support | |
| EASL | Marco Marzioni, MD | EASL |
| Forum | Veronica Miller, PhD* | Forum for Collaborative Research |
| Industry | Pam Vig* | Mirum Pharmaceuticals |
| Regulatory | Ruby Mehta | FDA/CDER/DHN |