On Wednesday, June 24, 2026, the Forum for Collaborative Research convened its 1st ACLF Forum as an online Zoom webinar.
Materials
Introductory Remarks and Program Overview
Welcome, Program Overview, and Acknowledgments
Meghan Rakowski, Forum for Collaborative Research
Veronica Miller, Forum for Collaborative Research
Richard Moreau, EF CLIF
Jacqueline O'Leary, Dallas VA Medical Center
Topic 1: Oncology and ACLF Parallels and Rationale
Why ACLF Drug Development is Unique - Clinician Perspectives
Jacqueline O'Leary, Dallas VA Medical Center
Why ACLF Drug Development is Unique - Industry Perspectives
Pejvack Motlagh, GENFIT
Topic II: Early Clinical Development Overview
Early Phase Studies in ACLF: Challenges in Recruitment and Assessment
Cornelius Engelmann, Charité – Universitätsmedizin Berlin
Dominique Thabut, AP-HP Sorbonne Université
Thomas Berg, Leipzig University Medical Center
Phase 1 Oncology Trials
Scott Berry, Berry Consultants
Utilizing Randomization, Backfill and Expansion Cohorts to Gain Greater Understanding in Phase 1 Trials
Alexia lasonos, Memorial Sloan Kettering Cancer Center
Q&A
All Participants
Topic III: Open Discussion
What Does and Does Not Transfer to ACLF
All Participants
Where to Start
All Participants
Wrap-Up
Closing Remarks
Veronica Miller, Forum for Collaborative Research
Richard Moreau, EF CLIF
Jacqueline O'Leary, Dallas VA Medical Center
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